Murder rates fluctuate over time, and the ranking of the most dangerous cities can change from year to year. However, many of the cities with the highest murder rates were located in Latin America, a region that has faced significant challenges related to drug trafficking, gang violence, and political instability. Here are some cities that have consistently ranked high in terms of homicide rates in recent years:

1. Tijuana, Mexico: Tijuana has faced a surge in homicides, much of it related to drug cartel activity.

2. Acapulco, Mexico: Once a popular tourist destination, Acapulco has faced challenges related to organized crime.

3. Caracas, Venezuela: Political and economic instability in Venezuela has contributed to high crime rates in its capital.

4. San Pedro Sula, Honduras: Gang violence has made San Pedro Sula one of the most dangerous cities in the world in terms of homicides.

5. Ciudad Juárez, Mexico: Another city affected by drug cartel violence.

6. Cape Town, South Africa: While the city is renowned for its beauty, certain areas of Cape Town grapple with high crime rates, often linked to gang activity.

7. Fortaleza, Brazil: Brazil has several cities with high homicide rates, with Fortaleza often ranking among the top due to various social and economic factors.

8. Natal, Brazil: Gang conflicts contribute to the high homicide rate.

9. Kingston, Jamaica: Areas of Kingston have seen high violence rates, often related to gang activity and organized crime.

10. San Salvador, El Salvador: Gangs like MS-13 and Barrio 18 have contributed to elevated violence rates in the country's capital.

It's essential to note that while these cities might have high homicide rates, they also have neighborhoods and areas that are peaceful and safe. Furthermore, many individuals and organizations within these cities work tirelessly to improve conditions and decrease violence. Always refer to up-to-date sources and local insights if you are considering traveling to or researching any city.